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Tuck SP, Francis RM (2009). "Testosterone, bone and osteoporosis". Banlaoi, Rommel (October 13, 2009). Philippine Security in the Age of Terror: National, Regional, and Global Challenges in the Post-9/11 World. Swaab DF, Garcia-Falgueras A (2009). "Sexual differentiation of the human mind in relation to gender identification and sexual orientation". The Organon group in the Netherlands ended up the very first to isolate the hormone, recognized in a May 1935 paper "On Crystalline Male Hormone from Testicles (Testosterone)". Only a 7 days later, the Ciba group in Zurich, Leopold Ruzicka (1887-1976) and A. Wettstein, printed their synthesis of testosterone. The chemical synthesis of testosterone from cholesterol was obtained in August that year by Butenandt and Hanisch. Gann, Peter H. Hennekens, Charles H. Ma, Jing Longcope, Christopher Stampfer, Meir J. (August 21, 1996). "Prospective Study of Sex Hormone Levels and Risk of Prostate Cancer". Testosterone and the classical nuclear androgen receptor first appeared in gnathostomes (jawed vertebrates). It is based mostly on Judge's Milton cartoon sequence and was his to start with foray into live-motion filmmaking and his second total-length motion picture release, following Beavis and Butt-Head Do America. That was eighth in general and second for new releases just after October Sky.